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. 2014 Jan 8;136(5):1706–1709. doi: 10.1021/ja410438n

Figure 2.

Figure 2

(A) PET and optical images of aqueous suspensions of QDs (nonradioactive), free 64CuCl2, mixture of 64CuCl2 and QDs, and 64Cu-doped QDs with the same amount of 64Cu radioactivity. (B) Comparison of the total photon flux extracted from the phantom images in (A). QDs without excitation light and 64Cu presence had virtually no photoluminescence. The total photon flux recorded from the IVIS system without emission filter followed the order of 64Cu-doped QDs > 64Cu mixed with QDs > 64Cu. (C–E) Photon flux obtained from 64Cu, mixture of 64Cu and QDs, 64Cu-doped QDs as well as QDs with QD526 (C), QD580 (D), and QD636 (E) under different emission filters versus the filter wavelengths. Increased photon flux at the emission wavelength of the QDs reflects effective Cerenkov resonance energy transfer (CRET).