Figure 7.

Magnetic nanoparticles (MNPs) in CTC capture and analysis. (a) Anti-EpCAM functionalized MNPs bind to CTCs and remove them from solution through the use of block magnets.⁷¹ Adapted with permission from ref (71). Copyright 2011 The Royal Society of Chemistry. (b) Schematic of an antibody modified using a heterofunctional linker and an immunomagnetic nanocarrier.⁷³ Adapted with permission from ref (73). Copyright 2013 American Chemical Society. (c) DSPE-PEG-NH₂ and C18-PMH-mPEG functionalized graphite-coated magnetic nanocrystals.⁷⁴ Adapted with permission from ref (74). Copyright 2013 American Chemical Society. (d) The magnetic moment of a MNP conjugated with a specific antibody is sensed as the MNP-covered cell flows over a series of micro-Hall sensors.⁷⁵ Adapted with permission from ref (75). Copyright 2012 American Association for the Advancement of Science.