Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(a) Barcode modulation of nanopore ionic current and multiplex detection of nucleic acid. Each target miRNA is hybridized with a PEG-labeled DNA probe. Upon being trapped in the nanopore, the PEG on the hybrid specifically regulates the nanopore current, thereby generating a signature for target identification. (b) Conjugation of a DNA probe with a PEG barcode through one-step copper(I)-catalyzed click chemistry.
