Table 1.
G-CSF Alone (n=13) |
Chemo + G-CSF (n=26) |
Total (n=39) |
|
---|---|---|---|
Median age (range) | 64y (55–73y) | 57y (42–68y) | 62y (26–73y) |
Diagnosis | |||
Non-Hodgkin lymphoma | 7 | 16 | 23 |
Hodgkin lymphoma | 0 | 1 | 1 |
Multiple Myeloma | 5 | 9 | 14 |
Amyloidosis | 1 | 0 | 1 |
Median # of prior regimens (range) | 2 (1–4) | 2 (1–8) | 2 (1–8) |
Prior lenalidomide (%) | 5 | 9 | 14 (36%) |
Prior fludarabine (%) | 0 | 2 | 2 (5%) |
Prior pelvic or spinal radiation | Spinal 2 Pelvic 1 |
Spinal 1 Pelvic 2 |
6 (15%) |
Prior failed mobilization (%) | 3 | 5 | 8 (21%) |
Prior ASCT (%) | 1 | 0 | 1 (3%) |
Reason for rescue use of plerixafor (%) | |||
Low blood CD34+ cell concentration | 8 | 22 | 30 (77%) |
Low initial apheresis CD34+ cell yield | 4 | 3 | 7 (18%) |
Waning apheresis CD34+ cell yield | 0 | 1 | 1 (3%) |
Clinical delay in apheresis | 1 | 0 | 1 (3%) |
Note: To provide complete data for each rescue use of plerixafor the one patient receiving 2 rescue attempts is listed twice.