Figure 4.

Intracranial injection: hPLAP protein expression profile and vector genome quantification. Animals received 1 ×109 vector genomes in 0.75 μl, administered bilaterally within the dorsal striatum via stereotaxic injection. hPLAP activity [in relative light units (RLU) per μg protein] (a) and quantification of vector genomes [vg per μg total DNA] (b) are reported. Data are presented as mean values ±SEM. (n=5) Scale bar: 50 μm. * indicates statistically significant difference compared to AAV6 (p<0.05).