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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: J Biomol NMR. 2013 Oct 17;57(3):281–296. doi: 10.1007/s10858-013-9788-9

Table 7.

Computation times of the three algorithms on the four test proteins on a 2.9 GHz Intel Core i7 MacBook Pro.

Method GB1 (56
residues)
HET-s (79
residues)
HNP-1 (30
residues)
Rhodopsin (98
residues)

MC/SA (20 steps) 25 min 25 min 25 min 25 min
NSGA-II 13 min 16 min 9 min 19 min
NSGA-II/MC 19 min - 2 min 23 min