Table 3.
Data for individual NSAIDs with OTC-dosage and prescription-strength (POM) formulations: data for exclusive users of OTC or POM formulations
| Ibuprofen | Ketoprofen | Diclofenac | Naproxen | |||||
|---|---|---|---|---|---|---|---|---|
| OTC | POM | OTC | POM | OTC | POM | OTC | POM | |
| n (% of all OTC or POM) | 41 178 (93.0%) | 3096 (7.0%) | 805 (1.8%) | 19 581 (16.2%) | 244 (0.5%) | 15 056 (12.4%) | 333 (0.7%) | 5052 (4.2%) |
| Age at first dispensation (years) | 39.8 | 40.6 | 44.7 | 45.2 | 49.8 | 52.6 | 45.6 | 46.6 |
| Gender female (%) | 55.8 | 52.3 | 53.3% | 44.5 | 62.7 % | 50.6 % | 62.8 % | 49.6% |
| Prevalent ALD | 18.8% | 19.0 % | 25.5% | 27.2% | 23.4% | 30.4% | 19.5% | 25.3% |
| Incident ALD | 2.5% | 1.9% | 2.4% | 3.3% | 2.0% | 4.0% | 3.3% | 3.2% |
| Cardiovascular drugs | 23.5% | 23.3% | 32.3% | 30.0% | 37.7% | 48.2% | 33.0% | 32.6% |
| Number of dispensations | 1.66 | 1.26 | 1.69 | 1.79 | 1.97 | 2.16 | 1.92 | 1.77 |
| One dispensation (%) | 70 | 87 | 79.3 | 73.5 | 79.5 | 70.3 | 78.4 | 77.9 |
| Two or three dispensations (%) | 23.9 | 10.9 | 13.8 | 19.7 | 11.2 | 19.1 | 12.3 | 16.4 |
| Four or more dispensations (5) | 6.1 | 2.1 | 7.0 | 6.8 | 8.6 | 10.7 | 9.3 | 6.7 |
| Total number of DDD dispensed | ||||||||
| Mean | 14.3 | 14.9 | 9.24 | 43.72 | 11.9 | 47.5 | 31.8 | 46.3 |
| Median | 6.67 | 10.0 | 3.33 | 20 | 3.75 | 22.5 | 8.8 | 17.6 |
| Distribution of number of DDD dispensed over 2 years (%) | ||||||||
| 1–7 | 52.1 | 0 | 81.9 | 0 | 67.6 | 0 | 0 | 0.5 |
| 7–14 | 26.9 | 79.9 | 8.3 | 9.8 | 19.7 | 2.7 | 66.1 | 0.2 |
| 14–21 | 10 | 13.4 | 3 | 58.6 | 4.1 | 36.1 | 17.4 | 63.8 |
| 21–28 | 3.3 | 0 | 1.2 | 1.3 | 2 | 28 | 3.9 | 3.4 |
| 1–30 | 93.6 | 96.4 | 94.9 | 69.8 | 93.9 | 74.3 | 87.4 | 69.1 |
| 30–60 | 4.1 | 2.2 | 2.7 | 20.9 | 2.5 | 12.6 | 4.5 | 20.2 |
| 60–90 | 0.9 | 0.5 | 1.1 | 2.7 | 1.6 | 4.7 | 2.1 | 4 |
| 90–120 | 0.4 | 0.4 | 0.4 | 2.2 | 0 | 1.7 | 0.6 | 1 |
| 120–150 | 0.3 | 0.1 | 0.1 | 0.6 | 0.8 | 1.2 | 0.6 | 1.3 |
| 150–180 | 0.2 | 0.1 | 0.1 | 0.8 | 0 | 1 | 1.5 | 0.8 |
| 180–210 | 0.1 | 0.1 | 0.4 | 0.4 | 0.4 | 0.6 | 0 | 0.4 |
| 210–240 | 0.1 | 0 | 0.2 | 0.4 | 0.4 | 0.5 | 0.9 | 0.2 |
| 240–270 | 0.1 | 0.1 | 0 | 0.2 | 0 | 0.5 | 0.3 | 0.4 |
| 270–300 | 0.1 | 0 | 0 | 0.2 | 0.4 | 0.3 | 0 | 0.2 |
| 300–330 | 0.1 | 0 | 0 | 0.2 | 0 | 0.2 | 0.3 | 0.1 |
| 330–360 | 0 | 0.1 | 0 | 0.2 | 0 | 0.3 | 0.3 | 0.1 |
| 360–390 | 0 | 0 | 0 | 0.1 | 0 | 0.3 | 0 | 0.2 |
| >390 DDD | 0.1 | 0.1 | 0 | 1.4 | 0 | 1.8 | 1.5 | 2 |
Abbreviations are as follows: ALD, chronic disease resulting in 100% coverage of medical expenses; DDD, defined daily dose; NSAID, nonsteroidal anti-inflammatory drug; OTC, over-the-counter preparations; and POM, prescription-only preparations.