Table 1.
Choroidal vasculature changes and choroidal thickness and volume values in convalescent VKH patients compared to controls
|
Patients |
Controls |
P value | |
|---|---|---|---|
| No. 13 (22 eyes) | No. 9 (17 eyes) | ||
| Choroidal thickness, mean ± SD (range), μm |
|
|
|
| Fovea |
200 ± 60 (54 to 305) |
288 ± 40 (229 to 350) |
<0.0001 (Student's t test) |
| Parafovea |
209 ± 61 (46 to 3.5) |
278 ± 36 (209 to 333) |
<0.0001 (Student's t test) |
| Entire macula |
198 ± 58 (44 to 282) |
268 ± 32 (202 to 318) |
<0.0001 (Student's t test) |
| Choroidal volume, mean ± SD (range), μm |
|
|
|
| Fovea |
0.99 ± 0.31 (0.21 to 1.49) |
1.49 ± 0.21 (1.17 to 1.82) |
<0.000 (Student's t test) |
| Parafovea |
1.28 ± 0.37 (0.29 to 1.9) |
1.75 ± 0.23 (1.32 to 2.11) |
<0.0001 (Student's t test) |
| Entire macula |
5.33 ± 1.60 (1.01 to 7.33) |
7.51 ± 0.93 (5.6 to 9.02) |
<0.0001 (Student's t test) |
| Preservation of choroidal vessel layers |
|
|
|
| Choriocapillaris-equivalent layer |
11/22 (50%) |
17/17 (100%) |
<0.000 (chi-square) |
| Medium choroidal vessels |
22/22 (100%) |
17/17 (100%) |
1 |
| Large choroidal vessels | 17/22 (77%) | 17/17 (100%) | <0.000 (chi-square) |
Choroidal thickness and volume values in the eyes with convalescent Vogt-Koyanagi-Harada disease were significantly lower than those in controls. Also, the choriocapillaris and large choroidal vessels were significantly lost in convalescent Vogt-Koyanagi-Harada disease.