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. 2014 Apr 29;9(4):e95406. doi: 10.1371/journal.pone.0095406

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© 2014 Guo et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The stability of PN(783)4.3 A) or PN(783)10.0 B) was examined by incubating nanoprobes for the indicated times and subjecting samples to FPLC. Arrows are the retention times of PN’s from Figure 2A , color coded as in that figure. Fluorochrome size is unchanged for both PN’s. C) Stability of PN fluorescence. PN(783)4.3 or PN(783)10.0 were incubated as indicated and fluorescence determined. D) Stability of ¹¹¹In binding to PN’s. ¹¹¹In-PN(783)4.3 or ¹¹¹In-PN(783)10.0 were incubated as indicated and radioactivity associated with the PN determined by HPLC. Exemplary chromatograms are provided; see Figure S6 in File S1.