Figure 2. Dose-response relationship between alanine aminotransferase level and relative risk of the metabolic syndrome.

Adjusted relative risks and 95% confidence intervals (CIs; dashed lines) are reported. ALT levels were modeled with restricted cubic splines with 3 knots in a random-effects dose-response model. The median value (6 U/L) of the lowest reference range was used to estimate all relative risks. The vertical axis is on a log scale; ALT, alanine aminotransferase.