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. 2014 Apr 29;9(4):e95959. doi: 10.1371/journal.pone.0095959

Figure 7. Intranasal treatment with BMP-7 reduces collagen-I expression in chronic asthmatic lungs.

Figure 7

Lung slides were stained with Masson's Trichrome (blue) and the morphometric analysis was performed as described in methods. Control (A), Chronic asthmatic (B), Chronic asthmatic treated with BMP-7 (300 µg/kg) by intranasal route (C). Morphometric analysis of the stained area (blue)(D). Data are representative of 5 animals in each of 3 independent experiments. Bars  = 50 µm. *p<0.05 comparing with the non asthmatic control; Δ p<0.05 comparing asthmatic mice treated or not with BMP-7.