Table 2. Multivariable models with eGFR as a continuous and dichotomous outcome (hyperfiltration).
eGFR Cystatin C | eGFR > 120 mL/min/1.73 m2 by Cystatin C | |||
β±SE** | p-value | OR, 95% CI*** | p-value | |
Non-stratified models | ||||
Glucose * | 0.14±0.04 | <0.0001 | 1.04 (1.01-1.07) | 0.02 |
No RAASi (No ACEi/ARB use) | ||||
Glucose * | 0.14±0.05 | 0.005 | 1.04 (1.00-1.09) | 0.03 |
RAASi (ACEi/ARB use) | ||||
Glucose * | 0.13±0.07 | 0.07 | 1.02 (0.96–1.09) | 0.43 |
*Multivariable models adjusted for gender, HbA1c, protein and sodium intake and ACEi/ARB use. **β-coefficient represents the difference in eGFR for every 10-unit increase for glucose (e.g., 10 mg/dL for blood glucose) in the independent variable, and difference for every 1-unit difference for the other variables.
***Odds ratios represent the average odds of hyperfiltration for every 10-unit increase in glucose, and for every 1-unit difference for the other variables.