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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Clin Immunol. 2014 Feb 13;152(0):36–47. doi: 10.1016/j.clim.2014.01.009

Figure 5.

Figure 5

A. Stimulation of sorted CD8+CD146+ T cells and CD8+CD146− T cells from healthy donors for 5 days in vitro with CD3/CD28 without the addition of any exogenous polarizing cytokines. PMA, ionomycin, and brefeldin A was added for the last 4 hours of this stimulation. Intracellular IFN-γ and IL-17A in CD8+CD146− T cells from a representative donor.

B. Intracellular IFN-γ and IL-17A in CD8+CD146+ T cells from a representative donor.

C. Composite results of these experiments from 14 healthy individuals. Significance was determined using the Wilcoxon matched pairs test and the bars indicate the mean SEM with 95% confidence intervals.