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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Clin Immunol. 2014 Feb 13;152(0):36–47. doi: 10.1016/j.clim.2014.01.009

Figure 6.

Figure 6

Supernatants from cultures of CD8+CD146− and CD146+ T cells from healthy individuals stimulated for 5 days with CD3/CD28 (as described in the text) analyzed by multiplex bead arrays for cytokine secretion in culture supernatant. CD8+ CD146+ compared to CD8+CD146–T cells demonstrated more Tc17-related cytokines after stimulation in vitro with only CD3/CD28. Significance was determined using the Wilcoxon matched pairs test and the bars indicate the mean SEM with 95% confidence intervals. Significantly more IL-17A and IL-17F were found in culture of CD8+CD146+ cells than in their CD146− counterparts, and significantly less TNF-α. Production of IL-22 trends higher in CD8+CD146+ cultures but did not reach significance at a level of 0.05.