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. Author manuscript; available in PMC: 2015 Jun 16.
Published in final edited form as: Eur J Pharm Sci. 2014 Jan 22;57:25–33. doi: 10.1016/j.ejps.2013.11.019

Table 4.

ECoG data from 60 second microdialysis sampling compared with that from 5 minute sampling (Table 1).

60 mg/kg bolus + 50 mg/kg/min infusion: 5 minute samplinga 60 mg/kg bolus + 50 mg/kg/min infusion: 60 second samplingb
Latency to Seizure Onset (s) 363.2 ± 148.8 438.0 ± 165.5
Number of Seizures Detected 592 ± 187 830 ± 62
Average of the Average Seizure Duration (s) 0.87 ± 1.78 0.6 ± 0.2
Rmax 71.8 ± 22.2 25.4 ± 1.5
a

: n = 12 rats

b

: n = 3 rats