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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Biotechnol Bioeng. 2013 Dec 28;111(6):1200–1209. doi: 10.1002/bit.25170

Figure 4. VSV production on PC3 IFIT2-ZsGreen reporter cells.

Figure 4

(A) Replication of both the rWT-DsRed-Ex and M51R-DsRed-Ex at MOI 50 was compared between the PC3 IFIT2-ZsGreen reporter cells and their PC3 progenitors. Virus production at 24 HPI was determined by plaque assay for 3 biological replicates. No significant difference was found for either WT or M51R between the two cells types (n.s. p> 0.1). However, we did observe a small but significant difference in viral production between the WT and M51R strains on the IFIT2 reporter cells (** p< 0.001, Student’s t-test)

(B) Replication kinetics of the VSV-WT-DsRed-Ex (filled triangles) and VSV-M51R-DsRed-Ex (filled circles) at MOI 50 on the PC-3 IFIT2-ZsGreen reporter cells. WT replication was higher than M51R at 8 and 24 HPI, but not at 4 and 12 HPI (** p<0.002, Student’s t-test).