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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Angiogenesis. 2013 Oct 29;17(3):563–571. doi: 10.1007/s10456-013-9403-4

Figure 1. Ganglioside depletion impedes tumor vascularization.

Figure 1

Panel A: Tumor growth (5 mice/group), representative of three separate experiments. Panel B: Visual appearance 10 days after s.c. injection of 10 6 WT or DKO cells. Panel C: Vasculature of the tumor site day 14 after injection (from left to right) of PBS (vehicle control), 105 WT, or 105 DKO cells. Panel D: Tumor histopathology (H&E stain), 10 days after injection of 106 cells. Upper: 50× magnification; lower: 400× magnification; left: WT tumor; right: DKO tumor.