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Specific activity of nisin, geobacillin I and the geobacillin I analogues generated in this study against B. subtilis ATCC6633.
| Peptide | IC50 (μM) | MIC (μM) |
|---|---|---|
| Nisin | 0.12 ± 0.01 | 0.25 |
| Geobacillin I | 0.56 ± 0.01 | 1.0 |
| Geobacillin-L19P | 1.00 ± 0.03 | 2.0 |
| Geobacillin-L19NVA | 5.70 ± 0.08 | 8.0 |
| Geobacillin-Dha5F/L6I | 0.45 ± 0.09 | 1.0 |
