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. Author manuscript; available in PMC: 2014 Apr 29.
Published in final edited form as: Int J Oncol. 2011 Jul 1;39(5):1205–1211. doi: 10.3892/ijo.2011.1111

Figure 4.

Figure 4

Status of miR-137 and miR-668 in organismal aging and HNSCC cell lines. (A and B) Age-dependent expression of miR-137 and miR-668 in vivo. Normal epithelial cells were microdissected from normal human oral epithelium. The levels of mature miR-137 (A) and miR-668 (B) expression were measured by quantitative real-time RT-PCR. R2, coefficient of determination. y, the equation of a line. (C and D) Downregulation of miR-137 and miR-668 expression in HNSCC. The levels of miR-137 (C) and miR-668 (D) were measured by quantitative real-time RT-PCR in normal and cancer cell lines. Two independent cultures of NHK (NHK-1 and -2) and six HNSCC cell lines (1483, SCC-4, SCC-9, SCC-15, Tu-139, and Tu-177) were used.