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. 2014 Mar 27;28(5):731–744. doi: 10.1210/me.2013-1425

Figure 1.

Figure 1.

Conditional loss of Notch2 results in decreased Prop1 mRNA at e12.5. Sagittal sections of control (A) and cKO (B) e12.5 pituitaries were stained with hematoxylin and eosin (H & E) and developing pituitaries appear to be roughly the same shape and size. Ki67 immunostaining is similar between control (C) and cKO (D) pituitaries. POMC is expressed in few cells in the pituitaries of control (E) and cKO (F) mice. The canonical Notch target Hey1 is expressed in the developing pituitary in control mice (G) and appears reduced in cKO mice (H). Prop1 is expressed in control mice (I) and appears reduced in cKO mice (J). Magnification, ×200. Bar, 50 μm. n = 4 to 6.