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LPS-induced inhibition of wet dog shake (WDS) behaviour in rats. Animals received a single i.p. dose of LPS (0.5 mg/kg) or saline and were allowed to recover for 6 h prior to a single subcutaneous injection of the 5-HT2A agonist DOI (1 mg/kg) or vehicle (saline). WDS behaviour was evaluated over a 20-minute period. Data represent mean ± SEM (n = 6/group), ***p < 0.001.
