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. 2004 May;24(10):4428–4437. doi: 10.1128/MCB.24.10.4428-4437.2004

TABLE 4.

Reduced fertility of male Nl1−/− mice

Parents (female × male) No. of productive matings Avg litter size (no. of pups)
+/− × +/+ 18 8.9
+/− × +/− 20 7.85
+/− × −/− 21 4.7a
+/+ × +/− 9 7.44
−/− × +/− 11 7.45
+/+ × +/+ 7 10.1
a

P = 0.0004 for variance between −/− and +/+ males and P = 0.0393 for variance between −/− and +/− males (one-way analysis of variance).