Table 1. Primary data of study groups.

Parameter	Intervention group (n = 601)	Control group (n = 601)	p-value
Age at reference time, mean (SD) [95% CI]	71.7 (±8.7) [71.0; 72.4]	72.2 (±9.0) [71.5; 72.9]	0.279*1
Male patients, % (n) [95% CI]	65.4 (393) [61.2; 69.2]	64.1 (385) [59.8; 67.7]	0.629*2
NYHA functional status, mean (SD) [95% CI]	2.16 (±0.6) [2.11; 2.20]	2.17 (±0.7) [2.11; 2.22]	0.619*1
Heart failure class, % (n)			0.761*2
NYHA I	9.5 (57)	15.3 (92)
NYHA II	67.7 (407)	55.2 (332)
NYHA III	20.3 (122)	26.6 (160)
NYHA IV	2.5 (15)	2.8 (17)

^*1t-test for independent samples; ^*2chi-square test; NYHA: New York Heart Association

95% CI: 95% confidence interval; mean: arithmetic mean; SD: standard deviation; n: number of patients