Methods	Randomised controlled trial.
Participants	97 pregnant women, 6-12 weeks’ gestation, with nausea for at least 1 week before trial entry 139 women responded to the study invitation, 97 women took part (symptoms disappeared, too ill, too late in pregnancy)
Interventions	Acupressure group: wristbands (with button/knob on the inside) day and night on Neigun point of both arms Placebo group: wristband (with felt patch in stead of button) identical on the outside to acupressure band 4 day run-in, 4 day intervention, 4 day follow up.
Outcomes	Symptoms of nausea and vomiting recorded daily - 3 recordings What problems they had: no problems, nausea, vomiting. How many hours they had suffered. Every evening an overall evaluation of their symptoms on a Visual Analogue Scale (0-5 no problems to worst thinkable level of nausea and vomiting)
Notes
Risk of bias
Item	Authors’ judgement	Description
Adequate sequence generation?	Yes	Block randomisation in blocks of 20.
Allocation concealment?	Unclear	Not stated.
Blinding? Change in grade of nausea or vomiting at second visit compared to first	Yes	A study assistant instructed the women in the use of the wristbands (investigators blinded)
Incomplete outcome data addressed? Change in grade of nausea or vomiting at second visit compared to first	Yes	All 97 participants reported on in results: 13 women who did not complete all of the daily forms were assigned values equivalent to the last reported value on the outcome variables
Free of selective reporting?	Unclear	Unclear about numbers per group in results tables (%s presented)
Free of other bias?	Yes	The authors highlight potential selection, information and performance of intervention bias - but these appear to be no greater than for other similar studies