Table 1. Antigens used to diagnose NCC by antibody capture.
| Test | Type of antigen | Sensitivity (1 lesion) | Sensitivity (>2 lesions) | Specificity | Cross-reactions | CSF better than serum | References |
| LLGP-EITB | Native semi-purified from whole cyst | ∼50% | 98% | 100% | No | No | [10,44,48,50,51,109,179] |
| rGP50-EITB | Recombinant from 50 kDa | N/E | 90%* | 100% | N/E | N/E | [53] |
| rGP50-ELISA | Recombinant from 50 kDa | N/E | 95%* | 94%* | No | Yes | [59] |
| rGP50-QuickELISA | Recombinant from 50 kDa | 42%* | 94%* | 99%* | No | N/E | [60] |
| rGP50-MAPIA | Recombinant from 50 kDa | 53% | 93% | 100% | No | N/E | [83] |
| rT24-EITB | Recombinant from 24 kDa | 63%* | 94%* | 98% | No | N/E | [54] |
| rT24-QuickELISA | Recombinant from 24 kDa | 47%* | 96%* | 99%* | No | N/E | [60] |
| rT24-MAPIA | Recombinant from 24 kDa | 60% | 97% | 99% | S. mansoni | N/E | [83] |
| rT24-MICT | Recombinant from 24 kDa | N/E | 94% | 99% | No | N/E | [180] |
| TsRS1-EITB | Synthetic from 8 kDa | 85%* | 96%* | 98% | N/E | N/E | [68] |
| TsRS1-ELISA | Synthetic from 8 kDa | 50%* | 77%* | 93% | N/E | N/E | [68] |
| TsRS1-FASTELISA | Synthetic from 8 kDa | N/E | 100%* | 100% | N/E | N/E | [61] |
| Ts18var1-EITB | Synthetic from 8 kDa | 35%* | 97%* | 100% | N/E | N/E | [68] |
| Ts18var1-ELISA | Synthetic from 8 kDa | 44%* | 95%* | 85% | N/E | N/E | [68] |
| Ts18var1-ELISA | Synthetic from 8 kDa | N/E | 90%* | 90%* | No | Yes | [59] |
| Ts18var1-FASTELISA | Synthetic from 8 kDa | N/E | 97%* | 100% | N/E | N/E | [61] |
| Ts18var1-QuickELISA | Synthetic from 8 kDa | 16%* | 90%* | 96%* | No | N/E | [60] |
| Ts8B2-ELISA | Recombinant from 8 kDa | N/E | 97% | 93% | Echinoccocosis Schistosomiasis | No | [72,73] |
| 10 kDa-EITB | Native 10 kDa from fluid cyst | N/E | 85%* | N/E | Echinoccocosis | N/E | [74] |
| 10 kDa-EITB | Recombinant from 10 kDa | N/E | 97%* | 98% | Echinoccocosis | N/E | [71] |
| 53/25 kDa EITB | Cathepsine L-like 53/25 kDa | 78%* | 96%* | 98%* | Echinococcosis | N/E | [77] |
| 53/25 kDa ELISA | Cathepsine L-like 53/25 kDa | 84%* | 98%* | 93%* | Echinococcosis T. saginata | N/E | [77] |
| 53/25 kDa dotELISA | Cathepsine L-like 53/25 kDa | 29.4%* | 84.8%* | 100%* | Echinococcosis | N/E | [78] |
Notes: NCC, neurocysticercosis; LLGP-EITB, lentil lectin glycoprotein enzyme-linked immunoelectrotransfer blot; CSF, cerebrospinal fluid; ELISA, enzyme-linked immunosorbent assay; MAPIA, multiantigen print immunoassay; MICT, Magnetic Immuno-Chromatographic Test; N/E, not evaluated.
*Calculated using sera with previously positive serology.