Table 2. Antibodies used to diagnose NCC by antigen capture.
Test | Type of antibody | Sensitivity (1 lesion) | Sensitivity (>2 lesions) | Specificity | Cross-reactions | CSF better than serum | References |
HP10-ELISA | MoAbs against T. saginata larval antigens from fluid and tegument of cyst | N/E | 75%** | 100%** | T. solium | No | [36,133] |
T. hydatigena | |||||||
B158/B60-ELISA | MoAbs against T. saginata excretory/secretory larval antigens | N/E | N/E | N/E | T. solium | Yes | [10,134,136,181] |
T. hydatigena |
Notes: NCC, neurocysticercosis; CSF, cerebrospinal fluid; ELISA, enzyme-linked immunosorbent assay; N/E, not evaluated.
**Calculated using only CSF.