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. 2012 Sep;106(5):299–304. doi: 10.1179/2047773212Y.0000000025

Table 1. Diagnostic criteria for neurocysticercosis13.

Diagnostic criteria
Absolute
• Histological demonstration of the parasite from biopsy of a brain or spinal cord lesion
• Evidence of cystic lesions showing the scolex on neuroimaging studies
• Direct visualization of subretinal parasites by fundoscopic examination
Major
• Evidence of lesions highly suggestive of neurocysticercosis on neuroimaging studies
• Positive serum immunoblot for the detection of anticysticercal antibodies
• Resolution of intracranial cystic lesions after therapy with albendazole or praziquantel
• Spontaneous resolution of small single enhancing lesions
Minor
• Evidence of lesions compatible with neurocysticercosis on neuroimaging studies
• Presence of clinical manifestations suggestive of neurocysticercosis
• Positive CSF ELISA for detection of anticysticercal antibodies or cysticercal antigens
• Evidence of cysticercosis outside the central nervous system
Epidemiological
• Individuals coming from or living in an area where cysticercosis is endemic
• History of travel to disease-endemic areas
• Evidence of a household contact with T. solium infection
Degrees of diagnostic certainty
Definitive
• Presence of one absolute criterion
• Presence of two major plus one minor and one epidemiological criteria
Probable
• Presence of one major plus two minor criteria
• Presence of one major plus one minor and one epidemiological criteria
• Presence of three minor plus one epidemiological criteria