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. 2014 Mar 12;4(1):29–38. doi: 10.5681/bi.2014.002

Table 2. Effect of polymers (CP:EC) ratio on the loading efficiency, production yield and particle siz e of Metformin Hydrochloride microparticles .

Formulations Carbomer :EC
ratio
Production
yield (%±SD)
Theoretical
drug Content (%)
Mean drug
Loading (%±SD)
Drug loading
efficiency (%±SD)
Mean particle Size
(µm±SD)
F1 1:2 89.64 ± 3.54 42.55 33.47 ± 1.78 78.66 ± 4.19 794.33 ± 25.11
F2 1:3 98.80 ± 6.07 33.33 32.81 ± 2.49 98.44 ± 6.98 933.25 ± 10.47
F3 1:4 85.74 ± 2.48 30.77 25.19 ± 2.37 81.87 ± 7.73 1071.52 ± 10.30