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PDH levels fall in response to AKI. PDH levels after AKI. By 18 hours after 30 minutes of unilateral ischemia, an approximately 55% reduction in renal cortical PDH was observed compared with normal kidney values (left panel). The uninjured CL kidney also had reduced PDH, but it remained significantly higher than its postischemic counterpart (P<0.04). As shown in right panel, glycerol-induced AKI also induced a significant PDH reduction (n=5 determinations each).
