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. 2004 May;48(5):1681–1687. doi: 10.1128/AAC.48.5.1681-1687.2004

TABLE 4.

Bacterial numbers in corneas infected with either MSSA or MRSA after late initiation of therapy

MSSA
MRSA
Expt No. of CFU/cornea (104)a
Expt No. of CFU/cornea (104)a
LasA Control LasA Vancomycin Control
I 190 1,500 I 0.75 10 67
30 960 0.006 1.4 54
0.21 54 0.008 <0.003 <0.003
0.007 2.3 7.2 28 78
0.05 180
<0.003 <0.003
II 0.07 33 II <0.003 0.01 49
0.01 190 <0.003 45 7.5
36 33 <0.003 3.5 0.2
80 576 <0.003 14.5 72
94 0.86
0.01 290
No. of eyes 12 12 8 8 8
Medianb 0.138 117 0.003 6.75 51.5
a

Values represent the results obtained for individual eyes in two independent experiments (Roman numerals), each of which was performed under identical conditions, with each experiment comprising either four (MRSA) or six (MSSA) rabbits per treatment group.

b

In calculating the median, numbers of CFU below <0.003 × 104 were considered zero (sterile corneas).