TABLE 2.
Infectivity of rSV(hHN) in micea
Virus dose (TCID50/mouse) | No. of survivors/total | Survival (%) | Mean day to death ± SD |
---|---|---|---|
105 | 15/15 | 100.0 | NA |
105.5 | 15/15 | 100.0 | NA |
106 | 12/15 | 80.0 | 18.5 ± 4.9 |
106.5 | 1/15b | 6.7 | 9.1 ± 1.2 |
107 | 0/5b | 0.0 | 7.8 ± 1.3 |
Mice infected with different virus doses were monitored for 21 days to determine the the number of mice that died and the mean day to death.
The number of mice who survived infection differed significantly from that of mock- infected mice (P < 0.05). NA, not applicable.