TABLE 4.
Strain | Assigned groupb | Geometric mean MIC | IC50 (μg/ml) ± SD |
---|---|---|---|
Rd | S | 0.16 | 0.18 ± 0.09 |
1369 | II | 2.83 | 1.77 ± 0.40 |
1312 | I | 10.29 | 0.96 ± 0.10 |
Rd/1312 | I(tx) | 1.74 | |
1311 | II | 8.00 | 2.92 ± 1.93 |
Rd/1311 | II(tx) | 2.21 |
Purified PBP3 proteins were incubated with unlabelled ampicillin, followed by Bocillin FL and penicillin.
S, ampicillin-susceptible H. influenzae Rd; I or II, class I or II PBP3; (tx), transformant of Rd containing full-length ftsI from clinical strains.