Table 4.
Locus HLA |
Bauru (n = 3542) (AF) |
Ribeirão Preto (n = 184) (AF) |
p-value | São Paulo (n = 239) (AF) |
p-value | Paraná (n = 2775) (AF) |
p-value | Rio Grande do Sul (n = 5000) (AF) |
p-value | Minas Gerais (n = 1000) (AF) |
p-value | Pernambuco (n = 101) (AF) |
p-value | Piauí (n = 97) (AF) |
p-value |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B*07 | 0.061 | 0.058 | 0.073 | 0.069 | 0.133 | 0.066 | 0.099 | 0.0423 | 0.206 | 0.0267 | |||||
B*08 | 0.050 | 0.049 | 0.036 | 0.055 | 0.118 | 0.0135 | 0.047 | 0.015 | 0.0339 | 0.144 | |||||
B*13 | 0.020 | 0.016 | 0.010 | 0.022 | 0.031 | 0.0293 | 0.016 | 0.020 | - | ||||||
B*14 | 0.051 | 0.077 | 0.0479 | 0.067 | 0.036 | 0.0001 | 0.103 | 0.060 | 0.049 | 0.052 | |||||
B*15 | 0.078 | 0.060 | 0.102 | 0.080 | 0.163 | 0.077 | 0.124 | 0.0283 | 0.186 | ||||||
B*35 | 0.120 | 0.126 | 0.089 | 0.0372 | 0.113 | 0.236 | 0.115 | 0.074 | 0.176 | ||||||
B*38 | 0.021 | 0.016 | 0.030 | 0.028 | 010142 | 0.048 | 0.015 | 0.005 | 0.052 | ||||||
B*40 | 0.047 | 0.047 | 0.040 | 0.048 | 0.098 | 0.037 | 0.0458 | 0.044 | 0.134 | ||||||
B*41 | 0.013 | 0.016 | 0.020 | 0.008 | 0.0036 | 0.021 | 0.018 | 0.015 | 0.001 | ||||||
B*42 | 0.012 | 0.025 | 0.005 | 0.004 | 0.0001 | 0.011 | 0.0001 | 0.025 | 0.0001 | 0.198 | 0.0001 | 0.052 | |||
B*45 | 0.014 | 0.011 | 0.020 | 0.010 | 0.0150 | 0.023 | 0.034 | 0.0001 | 0.030 | 0.031 | |||||
B*47 | 0.002 | - | 0 | 0.002 | 0.001 | 0.0001 | 0.002 | 0.015 | - | ||||||
B*48 | 0.005 | 0.005 | 0.005 | 0.005 | 0.013 | 0.003 | 0.030 | 0.0001 | - | ||||||
B*49 | 0.028 | 0.027 | 0.020 | 0.021 | 0.0069 | 0.054 | 0.031 | 0.040 | 0.052 | ||||||
B*53 | 0.021 | 0.027 | 0.040 | 0.0124 | 0.012 | 0.0001 | 0.030 | 0.0030 | 0.039 | 0.0001 | 0.035 | 0.083 | |||
B*54 | 0.001 | - | 0.005 | 0 | 0.0317 | - | - | ||||||||
B*55 | 0.009 | 0.008 | 0.010 | 0.021 | 0.013 | 0.005 | 0.031 | ||||||||
B*57 | 0.029 | 0.025 | 0.062 | 0.0001 | 0.031 | 0.058 | 0.037 | 0.040 | 0.001 | ||||||
B*58 | 0.024 | 0.036 | 0.005 | 0.0069 | 0.015 | 0.0002 | 0.040 | 0.030 | 0.025 | 0.083 | |||||
B*73 | 0.001 | - | 0 | 0 | 0.001 | 0.003 | 0.0463 | - | - | ||||||
B*81 | 0.002 | 0.011 | 0.0362 | 0 | 0.001 | 0.0192 | 0.0010 | 0.00010 | 0.0050 | - | 0.021 | ||||
B*82 | 0.001 | - | 0 | 0 | 0.001 | 0.001 | - | - |
HLA: human leukocyte antigen; AF: allele frequency; -: untyped alleles.
Statistical differences set for p-values ≤ 0.05.