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. Author manuscript; available in PMC: 2014 Apr 30.
Published in final edited form as: Annu Rev Med. 2009;60:417–430. doi: 10.1146/annurev.med.60.041707.170303

Figure 2.

Figure 2

Commercial system for MRgFUS treatment of brain tumors (Exablate 4000, Insightec, Haifa, Israel). (a) MR thermometry image showing focal heating during a clinical MRgFUS brain tumor treatment. (b) T2-weighted MRI with the focal heating superimposed. Exablate 4000 uses a hemispherical 1000-element phased-array transducer to sonicate through the intact skull, providing a completely noninvasive ablation method. The region between the scalp and the transducer is filled with chilled, degassed water to provide acoustic coupling and cooling. The phased array is used to steer the focal point to different locations and to correct skull-induced aberrations.

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