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. 2014 Mar;108(2):103–110. doi: 10.1179/2047773214Y.0000000131

Table 3. Comparison of the different case definitions.

2009 2011 2009 (with values of thrombocytopenia specified as less than 150 000) With backache included in the criteria of any 2 in the 2011 definition With backache included in the criteria of any 2 in the 2009 definition
Sensitivity 76.4 (69.6–82.1) 87.9 (82.2–91.9) 85.1 (79.0–89.6) 97.7 (94.2–99.1) 96.6 (95.4–97.8)
Specificity 42.5 (38.9–46.3) 20.1 (17.2–23.3) 32.5 (29.1–36.1) 9.3 (7.3–11.7) 14.3 (11.9–17.1)
LR+ 1.3 (1.2–1.5) 1.1 (1.0–1.2) 1.3 (1.2–1.4) 1.1 (1.0–1.1) 1.1 (1.0–1.2)
LR− 0.6 (0.4–0.7) 0.6 (0.4–0.9) 0.5 (0.3–0.7) 0.3 (0.1–0.7) 0.2 (0.1–0.5)
DOR 2.4 (1.6–3.5) 1.8 (1.1–3) 2.7 (1.7–4.3) 4.4 (1.6–12.2) 4.7 (2.0–10.9)

DOR: diagnostic odds ratio.