TABLE 3.
Enzymatic parameters of PBP2b*R6a
Variant | Relative value compared to penicillin IC50 (%)
|
k3 (s−1) for penicillin G | kcat/Km (M−1 · s−1) for S2d | |
---|---|---|---|---|
Piperacillin | Cefotaxime | |||
PBP2b* | 44 | >1,300 | 3.8 × 10−5 | 80 |
PBP2x* | 300 | 130 |
Data were obtained from two to three independent experiments.