Figure 4.

Fundus photographs in color (A), autofluorescence (B, C), and infrared ([D], left), and OCTs ([D], right) from two patients (upper block No. 1, D116 at the age of 47; lower block No. 2, D023 at the age of 39) with end-stage generalized choriocapillaris dystrophy characterized by semiconfluent multifocal areolar outer retinal atrophy, the severity of which decreases with increasing eccentricity. Central patches of visible sclera are surrounded by coarse confluent hyperpigmentation. The periphery shows isolated or clustered hyperpigmentation. In and around the fovea there is pronounced atrophy of the retinal pigment epithelium, the photoreceptor layer, and the outer nuclear layer and intraretinal hyperreflective material corresponding to the hyperpigmentation ([D2], white arrow).