Figure 3.

Transcription and translation efficiency affect expression noise. Genes that have noisier expression tend to have less efficient transcription (A) and increased translation efficiency (defined as the aggregated contribution of TIR and CDS sequence features) (B). The genes were subdivided into two groups: low- and high-noise differential genes, accordingly to the lower and upper quartile of their noise differential levels. High/low-noise differential genes have higher/lower than expected coefficient of variation given the mean expression. Mann–Whitney test significance: *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001.