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. Author manuscript; available in PMC: 2014 Apr 30.
Published in final edited form as: J Pediatr Endocrinol Metab. 2012;25(0):33–40. doi: 10.1515/jpem-2011-0450

Table 3.

Change in markers of carbohydrate and lipid metabolism.

Diet/exercise
Diet/exercise/metformin
6 months–0 month p-Value 6 months–0 month p-Value
Insulin, pmol/La 67±20 0.002 2±19 0.91
HOMA-IR 1.6±0.8 0.06 0.34±0.76 0.66
Adiponectin, mg/L 1.9±0.9 0.04 2.5±0.8 0.004
TC, mmol/L −0.20±0.11 0.1 0.03±0.10 0.82
LDL-C, mmol/L −0.14±0.09 0.14 −0.07±0.09 0.41
HDL-C, mmol/L 0.03±0.04 0.47 0.09±0.03 0.008
Triglycerides, mmol/L −0.002±0.09 0.15 −0.03±0.09 0.72
FFA, mmol/L −0.04±0.05 0.38 −0.01±0.4 0.88

Data are LS mean±SE.

a

p=0.02 between groups. To convert insulin to μIU/mL, divide by 6.945; low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and total cholesterol (TC) to mg/dL, divide by 0.0259; triglycerides to mg/dL, divide by 0.0113.