Figure 2. L. infantum infection elicits an acute phase response and chronic hepatocellular damage in rhesus macaques.

(A–B) Blood samples were collected for cellular enumeration at the indicated time points using a Coulter LH 500 hematology analyzer; (A) erythrocytes, (B) neutrophils. (C–F) Serum samples from rhesus macaques were collected at the indicated time points and the following analytes quantified; (C) c-reactive protein (CRP), (D) complement component 3 (C3), (E) complement component 4 (C4) and (F) alanine transaminase (ALT). Each dot represents an individual macaque. Statistics performed using one-way ANOVA followed by a Bonferroni's post-hoc test.