Table 2. Association of genetic polymorphism of IRF5 with acute rejection.
| SNPs of IRF5 | Genetic Model | Non-rejection | Acute Rejection | OR (95% CI) | P value |
| rs3757385 | |||||
| T/T | Cod | 105 (42.0%) | 11 (28.2%) | 1.00 | 0.078 |
| G/T | 109 (43.6%) | 17 (43.6%) | 1.49 (0.67–3.33) | ||
| G/G | 36 (14.4%) | 11 (28.2%) | 2.92 (1.17–7.30) | ||
| T/T | Do | 105 (42.0%) | 11 (28.2%) | 1.00 | 0.096 |
| G/T+G/G | 145 (58.0%) | 28 (71.8%) | 1.84 (0.88–3.87) | ||
| T/T+G/T | Re | 214 (85.6%) | 28 (71.8%) | 1.00 | 0.042 |
| G/G | 36 (14.4%) | 11 (28.2%) | 2.34 (1.07–5.10) | ||
| T/T+G/G | Ovd | 141 (56.4%) | 22 (56.4%) | 1.00 | 1.00 |
| G/T | 109 (43.6%) | 17 (43.6%) | 1.00 (0.51–1.97) | ||
| rs752637 | |||||
| T/T | Cod | 105 (42.0%) | 12 (30.8%) | 1.00 | 0.14 |
| C/T | 111 (44.4%) | 17 (43.6%) | 1.34 (0.61–2.94) | ||
| C/C | 34 (13.6%) | 10 (25.6%) | 2.57 (1.02–6.48) | ||
| T/T | Do | 105 (42.0%) | 12 (30.8%) | 1.00 | 0.18 |
| C/T+C/C | 145 (58.0%) | 27 (69.2%) | 1.63 (0.79–3.36) | ||
| T/T+C/T | Re | 216 (86.4%) | 29 (74.4%) | 1.00 | 0.067 |
| C/C | 34 (13.6%) | 10 (25.6%) | 2.19 (0.98–4.90) | ||
| T/T+C/C | Ovd | 139 (55.6%) | 22 (56.4%) | 1.00 | 0.92 |
| C/T | 111 (44.4%) | 13 (43.6%) | 0.97 (0.49–1.91) | ||
| rs11761199 | |||||
| A/A | Cod | 105 (42.0%) | 11 (28.2%) | 1.00 | 0.25 |
| A/G | 111 (44.4%) | 21 (53.9%) | 1.81 (0.83–3.93) | ||
| G/G | 34 (13.6%) | 7 (17.9%) | 1.97 (0.71–5.47) | ||
| A/A | Do | 105 (42.0%) | 11 (28.2%) | 1.00 | 0.096 |
| A/G+G/G | 145 (58.0%) | 28 (71.8%) | 1.84 (0.88–3.87) | ||
| A/A+A/G | Re | 216 (86.4%) | 32 (82.1%) | 1.00 | 0.48 |
| G/G | 34 (13.6%) | 7 (17.9%) | 1.39 (0.59–3.40) | ||
| A/A+G/G | Ovd | 139 (55.6%) | 18 (46.1%) | 1.00 | 0.27 |
| A/G | 111 (44.4%) | 21 (53.9%) | 1.46 (0.74–2.34) |
OR, odds ratio; CI, confidence intervals.
Cod, codominant; Do, dominant; Re, recessive; Ovd, overdominant.