TABLE 3.

Toxicity in H-9 cells of 4′-ethynyl D4T alone and in combination with other anti-HIV compounds as percentages of the results obtained with untreated controls^a

Additive and concn (μM)	% of results obtained with untreated controls at 4′-ethynyl D4T concn (μM) b of
	0	25	50
None	100 ± 5	97 ± 7	102 ± 6
LFd4C
5	73 ± 9	62 ± 3	72 ± 5
10	56 ± 4	58 ± 4	64 ± 5
3TC
5	99 ± 3	98 ± 2	99 ± 10
20	94 ± 3	88 ± 3	87 ± 6
100	108 ± 12	85 ± 3	84 ± 6

^aH-9 cells were grown for 48 h in the presence of single compounds or in combination as described in Materials and Methods.

^bThree or more wells for each condition were counted in duplicate using a Coulter counter. Numbers represent means and standard deviations obtained from three experiments.