Table 1.
Baseline demographic and clinical data of the two study groups
| m-TOR group (n = 30) | Control group (n = 58) | P value | |
|---|---|---|---|
|
Age (y) |
58.2 ± 13.7 |
54.5 ± 14 |
0.239 |
|
Gender (Male/Female) |
21/9 |
37/21 |
0.560 |
|
Cause of CKD |
|
|
|
|
(GN/PKD/HKD/IN/Other) |
9/4/1/3/13 |
23/4/6/9/16 |
0.370 |
|
Time from transplant to study end (mo) |
89.7 ± 72 |
82 ± 30 |
0.574 |
|
Systolic blood pressure (mm Hg) |
126 ± 11 |
130 ± 12 |
0.122 |
|
Diastolic blood pressure (mm Hg) |
73 ± 9 |
76 ± 8 |
0.129 |
|
Serum creatinine (mg/dL) |
1.56 ± 0.3 |
1.5 ± 0.4 |
0.464 |
|
No. of antihypertensive drugs |
1.6 ± 1 |
1.8 ± 0.8 |
0.224 |
|
Hemoglobin (g/dL) |
13 ± 1.5 |
13.6 ± 1.8 |
0.101 |
|
Cholesterol (mg/dL) |
177 ± 31 |
189 ± 40 |
0.124 |
|
Triglycerides (mg/dL) |
140 ± 60 |
165 ± 80 |
0.103 |
|
Uprot (mg/24 h) |
275 ± 232 |
32 ± 47 |
0.000 |
| BMI (kg/m 2 ) | 28 ± 4.7 | 28.3 ± 4.4 | 0.736 |
Values are shown as mean ± SD or absolute values. To convert creatinine in mg/dl to μmol/L, multiply by 88.4; Hemoglobin in g/dl to g/L, multiply by 10; cholesterol in mg/dL to mmol/L, multiply by 0.02586; triglycerides in mg/dL to mmol/L, multiply by 0.01129.
Abbreviations: IN, Interstitial nephropathy; CKD, chronic kidney disease; GN, glomerulonephritis; PKD, polycystic kidney disease; HKD, hypertensive kidney disease; IN, interstitial nephropathy; BMI, body mass index; Uprot, daily urinary protein excretion.