Table 2.

Distribution of GI symptoms in patients with ATTR amyloidosis

Symptom	Wild-type	TTR mutation
	n = 140	n = 1114
Any GI symptom	21 (15.3%)	696 (63.0%)
Early satiety	5 (3.6%)	291 (26.4%)
Nausea	3 (2.2%)	189 (17.1%)
Vomiting	0 (0.0%)	147 (13.4%)
Constipation	5 (3.6%)	230 (20.9%)
Diarrhea/constipation	2 (1.5%)	267 (24.3%)
Diarrhea	5 (3.6%)	218 (19.8%)
Fecal incontinence	0 (0.0%)	68 (6.2%)
Unintentional weight loss	4 (2.9%)	346 (31.5%)

Number of patients, n (%), reporting gastrointestinal (GI) symptoms at enrollment.