Table 5.
Standardised incidence ratios of second primary cancer by time since diagnosis
| |
|
|
Registry |
IARC/IACR |
SEER |
Registry‡ |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| First primary cancer | Time since diagnosis | SIR (95% CI) | SIR (95% CI) | SIR (95% CI) | SIR (95% CI) | |||||
| Lung cancer (C33-34) |
|
61 days- < 1 year |
0.55 |
(0.39, 0.76) |
0.47 |
(0.32, 0.66) |
0.38 |
(0.27, 0.53) |
0.58 |
(0.39, 0.82) |
| |
1-5 years |
0.98 |
(0.78, 1.22) |
0.88 |
(0.69, 1.11) |
0.95 |
(0.75, 1.18) |
1.04 |
(0.81, 1.32) |
|
| Colorectal cancer (C18-20) |
|
61 days- < 1 year |
0.79 |
(0.61, 1.00) |
0.73 |
(0.56, 0.94) |
0.78 |
(0.60, 0.99) |
0.81 |
(0.61, 1.04) |
| |
1-5 years |
0.93 |
(0.82, 1.05) |
0.86 |
(0.75, 0.98) |
0.93 |
(0.82, 1.05) |
0.88 |
(0.77, 1.01) |
|
| Prostate cancer (C61) |
|
61 days- < 1 year |
0.77 |
(0.61, 0.96) |
0.75 |
(0.59, 0.94) |
0.75 |
(0.59, 0.94) |
0.94 |
(0.74, 1.18) |
| |
1-5 years |
0.69 |
(0.61, 0.78) |
0.69 |
(0.61, 0.78) |
0.69 |
(0.61, 0.78) |
0.87 |
(0.77, 0.98) |
|
| Breast cancer (C50) |
age < 50 |
61 days- < 1 year |
1.05 |
(0.29, 2.70) |
0.53 |
(0.06, 1.90) |
0.79 |
(0.16, 2.31) |
1.11 |
(0.23, 3.25) |
| |
1-5 years |
2.32 |
(1.71, 3.07) |
1.11 |
(0.70, 1.66) |
2.22 |
(1.63, 2.96) |
1.77 |
(1.15, 2.62) |
|
| Breast cancer (C50) |
age ≥ 50 |
61 days- < 1 year |
0.75 |
(0.56, 0.98) |
0.65 |
(0.47, 0.87) |
0.68 |
(0.50, 0.90) |
0.84 |
(0.61, 1.13) |
| |
1-5 years |
0.91 |
(0.80, 1.02) |
0.70 |
(0.61, 0.81) |
0.88 |
(0.77, 1.00) |
1.16 |
(1.02, 1.32) |
|
| Head & neck (C00-C14, C30-C32) | |
61 days- < 1 year |
1.33 |
(0.91, 1.88) |
1.25 |
(0.84, 1.78) |
1.29 |
(0.88, 1.83) |
1.05 |
(0.67, 1.56) |
| 1-5 years | 2.10 | (1.80, 2.44) | 2.02 | (1.73, 2.36) | 2.07 | (1.77, 2.41) | 1.94 | (1.64, 2.27) | ||
‡excluding same site.
Abbreviations:SEER Surveillance Epidemiology and End Results, IARC International Agency for Research on Cancer, IACR International Association of Cancer Registries, SIR standardised incidence ratio, CI confidence interval.