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X-ray crystal structures of Escherichia coli and Mycobacterium tuberculosis CRPs in the absence and presence of cAMP. (a)E. coli apo-CRP (PDB ID 3HIF). (b)E. coli cAMP–CRP (PDB ID 2CGP). (c)M. tuberculosis apo-Rv3676 (PDB ID 3D0S). (d)M. tuberculosis cAMP-Rv3676 (PDB ID 3MZH). The diagram was constructed and the features are highlighted as described in the legend to Figure 1.
