Table 1.
Zebrafish Xenograft Data
Cell lines∗ | Graft-bearing embryos, N | Normal embryos, n (%) | Abnormal embryos, n (%) | Fibrotic reticulum |
---|---|---|---|---|
IPF primary mesenchymal cells† | 35 | 4 (11.4) | 31 (88.6) | Yes |
IPF MPCs | 43 | 36 (83.7) | 7 (16.3) | No |
IPF MPC-progeny | 65 | 7 (10.8) | 58 (89.2) | Yes |
Control primary mesenchymal cells† | 48 | 3 (6.3) | 45 (93.7) | No |
Control MPCs | 15 | 12 (80) | 3 (20) | No |
Control MPC-progeny | 95 | 14 (14.7) | 81 (85.3) | No |
MPCs, mesenchymal progenitor cells.
Data shown are from two IPF cell lines and two control cell lines.
In accord with our published data.16