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Representative sections of rat lungs in respect of 30 days treatment. (A) Normal rat lung showing normal alveoli and lung parenchyma; (B) 20 mg/kg/day HLE-FP-treated lung showing hyperplasia of the alveolar septae resulting in thickened alveolar space; (C) 100 mg/kg/day HLE-FP-treated lung showing alveolar space smaller than that of control; and (D) 500 mg/kg/day HLE-FP-treated lung showing alveolar space remarkably smaller than that of control (×100 magnification).
