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. 2014 Apr 23;5:78. doi: 10.3389/fphar.2014.00078

Table 1.

Effect of HLE-FP on body weight in the sub-chronic oral toxicity study.

Group 1st day 15th day 30th day 30th day 45th day 60th day 60th day
wt. (g) wt. (g) wt. (g) %Δwt. wt. (g) wt. (g) %Δwt.
I 120.40 ± 24.25 136.80 ± 17.24 159.10 ± 19.80 34.32 ± 18.47a 173.60 ± 18.00 187.40 ± 20.74 55.65 ± 25.06a
II 108.80 ± 7.45 134.70 ± 08.09 153.80 ± 21.04 41.67 ± 21.04 164.10 ± 18.19 191.20 ± 16.71 71.92 ± 09.57a
III 121.80 ± 17.10 144.00 ± 19.42 161.30 ± 18.71 28.02 ± 32.16a 165.90 ± 16.08 191.80 ± 23.51 69.02 ± 29.44a
IV 86.33 ± 23.40 129.30 ± 16.31 151.10 ± 12.40 85.62 ± 44.65 163.30 ± 11.05 175.20 ± 18.83 102.94 ± 15.50
a

Represents a significant decrease at p < 0.05 compared to control values (Group IV).

I, 500 mg/kg/day HLE-FP; II, 100 mg/kg/day HLE-FP; III, 20 mg/kg/day HLE-FP; IV, 10 ml/kg normal saline.