Figure 1.
Representative H&E Stains and Morphometry of Baseline WT and EphA2-R-M Hearts. WT (A) and EphA2-R-M (B) hearts from baseline mice were stained with H&E (20x). The LV cross-sectional area of the EphA2-R-M hearts was 40% smaller than WT hearts (p < 0.05). At baseline, LVID was 1.49 ± 0.09 mm and 1.44 ± 0.08 mm in B6 WT (n = 6) and EphA2-R-M (n = 7) mice, respectively. AWT was 14% less in EphA2-R-M (n = 7) hearts compared with WT (n = 6) hearts (*p < 0.01) (C). AWT, average wall thickness; LV, left ventricle; LVID, Left ventricular internal diameter.